癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
APM2 Rabbit Polyclonal Antibody
APM2 Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| IHC, IF |
|---|---|
| Primary Accession | Q15847 |
| Reactivity | Rat, Human, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 7855 Da |
| Gene ID | 10974 |
|---|---|
| Other Names | Adipogenesis regulatory factor, Adipogenesis factor rich in obesity, Adipose most abundant gene transcript 2 protein, Adipose-specific protein 2, apM-2, ADIRF, AFRO, APM2, C10orf116 |
| Dilution | IHC~~1:100~500 IF~~1:50~200 |
| Storage Conditions | -20℃ |
| Name | ADIRF |
|---|---|
| Synonyms | AFRO, APM2, C10orf116 |
| Function | Plays a role in fat cell development; promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation. Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed in adipose tissue (at protein level). Highly expressed in omental and subcutaneous adipose tissues. Expressed in heart, cornea, liver, kidney and spleen {ECO:0000269|PubMed:23239344, ECO:0000269|Ref.4} |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
APM2 gene is exclusively expressed in adipose tissue. Its function is currently unknown. [provided by RefSeq, Jul 2008],
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