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ATS3 Rabbit Polyclonal Antibody

ATS3 Rabbit Polyclonal Antibody

     
  • 1 - ATS3 Rabbit Polyclonal Antibody AP93496
    Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O15072
Reactivity Rat, Human, Mouse
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 135603 Da
Additional Information
Gene ID 9508
Other Names A disintegrin and metalloproteinase with thrombospondin motifs 3, ADAM-TS 3, ADAM-TS3, ADAMTS-3, 3.4.24.-, Procollagen II N-proteinase, PC II-NP, Procollagen II amino propeptide-processing enzyme, ADAMTS3, KIAA0366
Dilution WB~~1:1000
Storage Conditions-20℃
Protein Information
Name ADAMTS3
Synonyms KIAA0366
Function Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens.
Cellular Location Secreted. Secreted, extracellular space, extracellular matrix
Tissue Location Found in cartilage and skin.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016],

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