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SG1D1 Rabbit Polyclonal Antibody

SG1D1 Rabbit Polyclonal Antibody

     
  • 2 - SG1D1 Rabbit Polyclonal Antibody AP93480
    Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC, IF
Primary Accession O95968
Reactivity Rat, Human, Mouse
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 9898 Da
Additional Information
Gene ID 10648
Other Names Secretoglobin family 1D member 1, Lipophilin-A, SCGB1D1, LIPHA, LPNA
Dilution IHC~~1:100~500
IF~~1:50~200
Storage Conditions-20℃
Protein Information
Name SCGB1D1
Synonyms LIPHA, LPNA
Function May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.
Cellular Location Secreted.
Tissue Location Expressed in lachrymal gland, thymus, kidney, testis, ovary and salivary gland
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. This gene product represents one component of a heterodimeric molecule present in human tears whose elution profile is consistent with prostatein, a tetrameric molecule composed of three peptide components in heterodimers. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 15, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008],

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