癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
ZPBP1 Rabbit Polyclonal Antibody
ZPBP1 Rabbit Polyclonal Antibody
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- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q9BS86 |
| Reactivity | Human, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 40142 Da |
| Gene ID | 11055 |
|---|---|
| Other Names | Zona pellucida-binding protein 1, Inner acrosomal membrane IAM38, Sp38, ZPBP, ZPBP1 |
| Dilution | WB~~1:1000 |
| Storage Conditions | -20℃ |
| Name | ZPBP |
|---|---|
| Synonyms | ZPBP1 |
| Function | Plays a role in acrosome compaction and sperm morphogenesis (PubMed:21911476). Is implicated in sperm-oocyte interaction during fertilization (By similarity). |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:Q62522}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q62522}. Secreted. Note=First localized in acrosome granule, later migrates to the inner and outer acrosomal membrane. Released after the acrosomal reaction {ECO:0000250|UniProtKB:Q62522} |
| Tissue Location | Expressed specifically in testis. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida (McLeskey et al., 1998 [PubMed 9378618]).[supplied by OMIM, Aug 2008],
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