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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   Aggrecan Antibody   

Aggrecan Antibody

Rabbit mAb

     
  • 2 - Aggrecan Antibody AP91314
    Immunohistochemical analysis of paraffin-embedded human cartilage tissue, using Aggrecan Antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC
Primary Accession P16112
Reactivity Human
Clonality Monoclonal
Other Names ACAN; AGC1; AGCAN; Aggrecan 1; CSPG1; CSPGCP; JSCATE; Large aggregating proteoglycan; mcspg; mgsk16; MSK 16; SEDK;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 261329 Da
Additional Information
Dilution IHC 1:50~1:200
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human Aggrecan
Description Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name ACAN
Synonyms AGC1, CSPG1, MSK16
Function This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.
Cellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P07898}
Tissue Location Detected in fibroblasts (at protein level) (PubMed:36213313). Restricted to cartilage (PubMed:7524681)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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