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>   首页   >   产品   >   一抗   >   心血管   >   AMPD3 Antibody (Center)   

AMPD3 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - AMPD3 Antibody (Center) AP7869c
    AMPD3 Antibody (Center) (Cat.# AP7869c) western blot analysis in human placenta tissue lysate (35ug/lane). This demonstrates that the AMPD3 antibody detected AMPD3 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q01432
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 88812 Da
Antigen Region 325-356 aa
Additional Information
Gene ID 272
Other Names AMP deaminase 3, AMP deaminase isoform E, Erythrocyte AMP deaminase, AMPD3
Target/Specificity This AMPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the Central region of human AMPD3.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAMPD3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AMPD3 (HGNC:470)
Function AMP deaminase plays a critical role in energy metabolism.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

AMPD3 is a member of the AMP deaminase gene family. This protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. The protein is the erythrocyte (E) isoforms, whereas other family members isoforms predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency.

REFERENCES

Mahnke-Zizelman D.K., Eddy R.Biochim. Biophys. Acta 1306:75-92(1996)
Yamada Y., Goto H., Wakamatsu N., Ogasawara N.Hum. Mutat. 17:78-78(2001)

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