CD79b Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB, IHC-P, IF, FC, ICC, IP |
---|---|
Primary Accession | P40259 |
Reactivity | Rat, Human, Mouse |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Isotype | IgG |
Conjugate | Unconjugated |
Immunogen | A synthesized peptide derived from human CD79b |
Purification | Affinity Chromatography |
Calculated MW | 26048 Da |
Gene ID | 974 |
---|---|
Other Names | CD79B |
Dilution | WB~~1/500-1/1000 IHC-P~~N/A IF~~1:50~200 FC~~1:10~50 ICC~~N/A IP~~N/A |
Format | Liquid in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Name | CD79B |
---|---|
Synonyms | B29, IGB |
Function | Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts. |
Tissue Location | B-cells. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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Cat# AP77906