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>   首页   >   产品   >   一抗   >   其他   >   P2Y6 Rabbit mAb   

P2Y6 Rabbit mAb

     
  • 1 - P2Y6 Rabbit mAb AP74869
    Immunocytochemistry analysis of P2Y6 (green) in A549 using P2Y6 antibody,and DAPI(blue).
  • 2 - P2Y6 Rabbit mAb AP74869
    Western blot analysis of P2Y6 in K562, Hela lysates using P2Y6 antibody.
  • 8 - P2Y6 Rabbit mAb AP74869
    Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using P2Y6 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IP
Primary Accession Q15077
Reactivity Human
Host Rabbit
Clonality Monoclonal Antibody
Isotype IgG
Conjugate Unconjugated
Purification Affinity Purified
Calculated MW 36429 Da
Additional Information
Gene ID 5031
Other Names P2RY6
Dilution WB~~1:1000-1:5000
IHC-P~~1:50~200
IP~~1:20-1:50
Format Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Protein Information
Name P2RY6
Function Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

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