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Epiregulin Polyclonal Antibody

     
  • 14 - Epiregulin Polyclonal Antibody AP74228
    Immunohistochemical analysis of paraffin-embedded Human-liver, antibody was diluted at 1:100
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P
Primary Accession O14944
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 19044 Da
Additional Information
Gene ID 2069
Other Names Proepiregulin [Cleaved into: Epiregulin (EPR)]
Dilution IHC-P~~IHC-p 1:50-200, ELISA 1:10000-20000
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name EREG
Function Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357).
Cellular Location [Epiregulin]: Secreted, extracellular space
Tissue Location In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357).

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