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Imp3 Polyclonal Antibody

     
  • 1 - Imp3 Polyclonal Antibody AP73996
    Western Blot analysis of HEPG2 cells using Antibody diluted at 1000. Secondary antibody was diluted at 1:20000
  • 14 - Imp3 Polyclonal Antibody AP73996
    Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
  • 14 - Imp3 Polyclonal Antibody AP73996
    Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
  • 14 - Imp3 Polyclonal Antibody AP73996
    Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200
  • 14 - Imp3 Polyclonal Antibody AP73996
    Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9NV31
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 21850 Da
Additional Information
Gene ID 55272
Other Names IMP3 C15orf12 MRPS4
Dilution WB~~WB 1:500-2000, ELISA 1:10000-20000
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name IMP3 (HGNC:14497)
Synonyms C15orf12, MRPS4
Function Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
Cellular Location Nucleus, nucleolus
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.

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