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Anti-FTH1 Antibody

Rabbit polyclonal antibody to FTH1

     
  • 1 - Anti-FTH1 Antibody AP60462
    Western blot analysis of FTH1 expression in LO2 (A), C6 (B), MEF (C), U87MG (D), HepG2 (E) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P02794
Other Accession P09528
Reactivity Human, Mouse, Rat, Rabbit, Monkey, Drosophila
Host Rabbit
Clonality Polyclonal
Calculated MW 21226 Da
Additional Information
Gene ID 2495
Other Names FTH; FTHL6; Ferritin heavy chain; Ferritin H subunit; Cell proliferation-inducing gene 15 protein
Target/Specificity Recognizes endogenous levels of FTH1 protein.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name FTH1
Synonyms FTH, FTHL6
Function Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed:9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed:9003196). Also plays a role in delivery of iron to cells (By similarity). Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed:24695223, PubMed:26436293).
Cellular Location Cytoplasm. Lysosome. Cytoplasmic vesicle, autophagosome
Tissue Location Expressed in the liver.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FTH1. The exact sequence is proprietary.

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