癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
MTX1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q13505 |
| Reactivity | Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 51463 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human MTX1 |
| Epitope Specificity | 301-400/466 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Membrane. Mitochondrion outer membrane. |
| SIMILARITY | Belongs to the metaxin family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Metaxin 1 is a 317 amino acid member of the Metaxin protein family. Localized to the mitochondrion outer membrane, Metaxin 1 is involved in the transport of proteins into the mitochondrion. Metaxin 1 is also believed to be essential for embryonic development. Metaxin 1 has been found to interact with other Metaxin family members, including Metaxin 2. Although ubiquitously expressed, highest levels of Metaxin 1 are present in kidney. The gene that encodes Metaxin 1 maps to human chromosome 1, which is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. |
| Gene ID | 4580 |
|---|---|
| Other Names | Metaxin-1, Mitochondrial outer membrane import complex protein 1, MTX1, MTX, MTXN |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4) with 1% BSA, 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | MTX1 |
|---|---|
| Synonyms | MTX, MTXN |
| Function | Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity). |
| Cellular Location | Membrane; Single-pass type I membrane protein. Mitochondrion outer membrane |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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