癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
AMY2A Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, E |
|---|---|
| Primary Accession | P04746 |
| Other Accession | P00690, P19961, P04745, NP_000690.1 |
| Reactivity | Human, Mouse |
| Predicted | Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 57707 Da |
| Antigen Region | 484-511 aa |
| Gene ID | 279 |
|---|---|
| Other Names | Pancreatic alpha-amylase, PA, 4-alpha-D-glucan glucanohydrolase, AMY2A |
| Target/Specificity | This AMY2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-511 amino acids from the C-terminal region of human AMY2A. |
| Dilution | WB~~1:1000 IF~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | AMY2A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AMY2A |
|---|---|
| Cellular Location | Secreted, extracellular space. |
| Tissue Location | Detected in pancreas (at protein level). |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.
REFERENCES
Endo, T., et al. Diabetes 58(3):732-737(2009)
Baltova, S.D. Folia Med (Plovdiv) 47(1):37-41(2005)
Scheil, H.G., et al. Anthropol Anz 62(4):429-434(2004)
Numao, S., et al. J. Biol. Chem. 279(46):48282-48291(2004)
Baltova, S., et al. Coll Antropol 28 SUPPL 2, 291-295 (2004) :
Jacob, M., et al. Biochem. Cell Biol. 70 (10-11), 1105-1114 (1992) :
Groot, P.C., et al. Genomics 8(1):97-105(1990)
Horii, A., et al. Gene 60(1):57-64(1987)
Nishide, T., et al. Gene 41 (2-3), 299-304 (1986) :
Kaczmarek, M.J., et al. Clin. Chim. Acta 79(1):69-73(1977)
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