NT5C1A Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, IF |
---|---|
Primary Accession | Q9BXI3 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | polyclonal |
Calculated MW | 41021 Da |
Gene ID | 84618 |
---|---|
Other Names | Cytosolic 5'-nucleotidase 1A, cN1A, Cytosolic 5'-nucleotidase IA, cN-I, cN-IA, NT5C1A |
Dilution | WB~~ 1:1000 IF~~1:100 |
Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol. |
Storage Conditions | -20℃ |
Name | NT5C1A |
---|---|
Function | Catalyzes the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside (PubMed:11133996, PubMed:34814800, PubMed:7599155, PubMed:8967393). AMP is the major substrate but can also hydrolyze dCMP and IMP (PubMed:11133996, PubMed:34814800, PubMed:7599155, PubMed:8967393). |
Cellular Location | Cytoplasm. |
Tissue Location | Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.
REFERENCES
Hunsucker S.A.,et al.J. Biol. Chem. 276:10498-10504(2001).
Lowenstein J.M.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).

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