LLGL2 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, E |
---|---|
Primary Accession | Q6P1M3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 113448 Da |
Antigen Region | 940-973 aa |
Gene ID | 3993 |
---|---|
Other Names | Lethal(2) giant larvae protein homolog 2, HGL, LLGL2 |
Target/Specificity | This LLGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 940-973 amino acids from the C-terminal region of human LLGL2. |
Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LLGL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LLGL2 |
---|---|
Function | Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par- 6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity. |
Cellular Location | Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell- cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
REFERENCES
Yasumi, M., et al., J. Biol. Chem. 280(8):6761-6765 (2005). Katoh, M., et al., Int. J. Oncol. 24(3):737-742 (2004).

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问,联系:0512-88856768 tech-china@abcepta.com.