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CNP Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - CNP Antibody (C-Term) AP21585b
    All lanes : Anti-CNP Antibody (C-Term) at 1:2000 dilution Lane 1: mouse brain lysates Lane 2: rat brain lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - CNP Antibody (C-Term) AP21585b
    All lanes : Anti-CNP Antibody (C-Term) at 1:2000 dilution Lane 1: human brain lysates Lane 2: human cerebellum lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P09543
Reactivity Human, Rat, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 47579 Da
Additional Information
Gene ID 1267
Other Names 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, CNPase, CNP
Target/Specificity This CNP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 122-156 amino acids from human CNP.
Dilution WB~~1:2000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCNP Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNP (HGNC:2158)
Function Catalyzes the formation of 2'-nucleotide products from 2',3'- cyclic substrates (By similarity). May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity).
Cellular Location Membrane {ECO:0000250|UniProtKB:P16330}; Lipid- anchor {ECO:0000250|UniProtKB:P16330}. Melanosome. Note=Firmly bound to membrane structures of brain white matter. {ECO:0000250|UniProtKB:P16330}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.

REFERENCES

Thompson R.J.,et al.Biochem. Soc. Trans. 20:621-626(1992).
Kurihara T.,et al.Biochem. Biophys. Res. Commun. 152:837-842(1988).
Monoh K.,et al.Gene 129:297-301(1993).
Douglas A.J.,et al.Ann. Hum. Genet. 56:243-254(1992).
Zody M.C.,et al.Nature 440:1045-1049(2006).

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