RRH Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application
| WB, E |
|---|---|
| Primary Accession | O14718 |
| Other Accession | NP_006574.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 37423 Da |
| Antigen Region | 213-240 aa |
| Gene ID | 10692 |
|---|---|
| Other Names | Visual pigment-like receptor peropsin, RRH |
| Target/Specificity | This RRH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the C-terminal region of human RRH. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RRH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RRH |
|---|---|
| Function | May play a role in rpe physiology either by detecting light directly or by monitoring the concentration of retinoids or other photoreceptor-derived compounds. |
| Cellular Location | Membrane; Multi-pass membrane protein |
| Tissue Location | Found only in the eye, where it is localized to the retinal pigment epithelium (RPE). In the RPE, it is localized to the microvilli that surround the photoreceptor outer segments |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes opsin 5 and retinal G protein coupled receptor. [provided by RefSeq].
REFERENCES
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)
Rivolta, C., et al. Mol. Vis. 12, 1511-1515 (2006) :
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Bellingham, J., et al. BMC Genomics 4 (1), 3 (2003) :
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