癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CEACAM8 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | P31997 |
| Other Accession | NP_001807.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38154 Da |
| Antigen Region | 53-81 aa |
| Gene ID | 1088 |
|---|---|
| Other Names | Carcinoembryonic antigen-related cell adhesion molecule 8, CD67 antigen, Carcinoembryonic antigen CGM6, Non-specific cross-reacting antigen NCA-95, CD66b, CEACAM8, CGM6 |
| Target/Specificity | This CEACAM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the N-terminal region of human CEACAM8. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CEACAM8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CEACAM8 (HGNC:1820) |
|---|---|
| Function | Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:11590190, PubMed:2022629, PubMed:8776764). Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:11590190, PubMed:2022629, PubMed:8776764). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764). |
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. Cell surface |
| Tissue Location | Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Lasa, A., et al. Ann. Hematol. 87(3):205-211(2008)
Skubitz, K.M., et al. J Transl Med 6, 78 (2008) :
Yoon, J., et al. J. Immunol. 179(12):8454-8462(2007)
Ordonez, C., et al. J. Cell. Physiol. 210(3):757-765(2007)
Ramachandran, P., et al. J. Proteome Res. 5(6):1493-1503(2006)
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¥ 1,250.00
Cat# AP16488a
