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>   首页   >   产品   >   一抗   >   发育生物学   >   DPPA4 Antibody (N-term)   

DPPA4 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - DPPA4 Antibody (N-term) AP1438a
    Western blot analysis of DPPA4 Antibody (N-term) (Cat. #AP1438a) in CEM cell line lysates (35ug/lane). DPPA4 (arrow) was detected using the purified Pab.
  • 14 - DPPA4 Antibody (N-term) AP1438a
    Formalin-fixed and paraffin-embedded human testis tissue reacted with DPPA4 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession Q7L190
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 33541 Da
Antigen Region 50-79 aa
Additional Information
Gene ID 55211
Other Names Developmental pluripotency-associated protein 4, DPPA4
Target/Specificity This DPPA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human DPPA4.
Dilution WB~~1:1000
IHC-P~~1:100~500
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDPPA4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DPPA4
Function May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic cells into a primitive ectoderm lineage.
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q8CCG4}. Note=Associated with transcriptionally active chromatin {ECO:0000250|UniProtKB:Q8CCG4}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

DppA4 is a member of the Dppa family of developmental pluripotency associated transcription factors. Dppa4 is a target of Oct4, Sox2 and Nanog. It may play a role in maintaining cell pluripotentiality.

REFERENCES

Bortvin,A., Development 130 (8), 1673-1680 (2003

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