ADSS Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, E |
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Primary Accession | P30520 |
Other Accession | NP_001117.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 50097 Da |
Antigen Region | 396-422 aa |
Gene ID | 159 |
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Other Names | Adenylosuccinate synthetase isozyme 2 {ECO:0000255|HAMAP-Rule:MF_03127}, AMPSase 2 {ECO:0000255|HAMAP-Rule:MF_03127}, AdSS 2 {ECO:0000255|HAMAP-Rule:MF_03127}, 6344 {ECO:0000255|HAMAP-Rule:MF_03127}, Adenylosuccinate synthetase, acidic isozyme {ECO:0000255|HAMAP-Rule:MF_03127}, Adenylosuccinate synthetase, liver isozyme {ECO:0000255|HAMAP-Rule:MF_03127}, L-type adenylosuccinate synthetase {ECO:0000255|HAMAP-Rule:MF_03127}, IMP--aspartate ligase 2 {ECO:0000255|HAMAP-Rule:MF_03127}, ADSS {ECO:0000255|HAMAP-Rule:MF_03127} |
Target/Specificity | This ADSS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-422 amino acids from the C-terminal region of human ADSS. |
Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ADSS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADSS2 (HGNC:292) |
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Function | Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. |
Cellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03127}. Mitochondrion {ECO:0000250|UniProtKB:A4Z6H1}. Note=Partially associated with particulate fractions |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.
REFERENCES
Sivendran, S., et al. Protein Sci. 17(7):1162-1174(2008)
Zhang, F., et al. BMC Med. Genet. 9, 119 (2008) :
Zhang, F., et al. Behav Brain Funct 4, 39 (2008) :
Sun, H., et al. Mol. Cell. Biochem. 269 (1-2), 85-94 (2005) :
Stepinski, J., et al. Kidney Int. 50(4):1195-1201(1996)

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