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CD137

Purified Mouse Monoclonal Antibody

     
  • 10 - CD137 AO2696a
    Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
  • 1 - CD137 AO2696a
    Figure 2:Western blot analysis using CD137 mAb against human CD137 (AA: extra 24-186) recombinant protein. (Expected MW is 47.1 kDa)
  • 51 - CD137 AO2696a
    Figure 3:Flow cytometric analysis of Ramos cells using CD137 mouse mAb (green) and negative control (red).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, ICC, E
Primary Accession Q07011
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4C1A9
Isotype Mouse IgG1
Calculated MW 27899 Da
Immunogen Purified recombinant fragment of human CD137 (AA: extra 24-186) expressed in HEK293 cells.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 3604
Other Names TNFRSF9; ILA; 4-1BB; CDw137
Dilution WB~~ 1/500 - 1/2000
IHC~~1:100~500
ICC~~N/A
E~~ 1/10000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD137 is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFRSF9
Synonyms CD137, ILA
Function Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed on the surface of activated T-cells.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

1.Clin Cancer Res. 2014 Jan 1;20(1):44-55.2.Cancer Res. 2013 Jan 15;73(2):652-61.

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