癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
GAST Antibody(Ascites)
Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | P01350 |
| Other Accession | NP_000796.1 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone Names | 486CT4.8.13.6 |
| Calculated MW | 11394 Da |
| Antigen Region | 49-78 aa |
| Gene ID | 2520 |
|---|---|
| Other Names | Gastrin, Gastrin-71, Gastrin component I, Gastrin-52, G52, Big gastrin, Gastrin component II, Gastrin-34, G34, Gastrin, Gastrin component III, Gastrin-17, G17, Gastrin-14, G14, Gastrin-6, G6, GAST, GAS |
| Target/Specificity | This GAST antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from human GAST. |
| Dilution | WB~~1:100~1600 E~~Use at an assay dependent concentration. |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GAST Antibody(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GAST |
|---|---|
| Synonyms | GAS |
| Function | Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. |
| Cellular Location | Secreted. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq].
REFERENCES
Kovac, S., et al. FEBS Lett. 584(21):4413-4418(2010)
Ferrand, A., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (1), G220-G227 (2010) :
El Ali, Z., et al. J. Endocrinol. Invest. 33(3):186-191(2010)
Huang, C.L., et al. Pharmacology 85(3):131-135(2010)
Leja, M., et al. Dig. Dis. Sci. 54(11):2377-2384(2009)
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