癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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CHRNE antibody - N-terminal region
Rabbit Polyclonal Antibody
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- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q04844 |
| Other Accession | NM_000080, NP_000071 |
| Reactivity | Mouse, Rat, Pig, Guinea Pig |
| Predicted | Mouse, Rat, Pig, Guinea Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 54697 Da |
| Gene ID | 1145 |
|---|---|
| Alias Symbol | ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS |
| Other Names | Acetylcholine receptor subunit epsilon, CHRNE, ACHRE |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-CHRNE antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | CHRNE antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CHRNE (HGNC:1966) |
|---|---|
| Synonyms | ACHRE |
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
| Cellular Location | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
REFERENCES
Beeson D.M.W.,et al.Eur. J. Biochem. 215:229-238(1993).
Abicht A.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Gomez C.M.,et al.Neurology 45:982-985(1995).
Ohno K.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:758-762(1995).
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