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C1QL3 Antibody - middle region

Rabbit Polyclonal Antibody

     
  • 1 - C1QL3 Antibody - middle region AI15561

    Host: Rabbit
    Target Name: C1QL3
    Sample Tissue: A549 Whole cell lysate
    s
    Antibody Dilution: 1.0μg/ml
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q5VWW1
Other Accession NP_001010908
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 26719 Da
Additional Information
Gene ID 389941
Alias Symbol C1QL3, CTRP13,
Other Names Complement C1q-like protein 3, C1q and tumor necrosis factor-related protein 13, C1q/TNF-related protein 13, C1QL3, CTRP13
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-C1QL3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsC1QL3 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C1QL3
Synonyms CTRP13
Function May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production (By similarity).
Cellular Location Secreted.
Tissue Location Highly expressed in adipose tissue, with expression levels at least 2 orders of magnitude higher than in other tissues, including brain and kidney.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Deloukas P.,et al.Nature 429:375-381(2004).
Wei Z.,et al.J. Biol. Chem. 286:15652-15665(2011).

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