CTDSP1 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application ![]()
| WB |
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Primary Accession | Q9GZU7 |
Other Accession | NM_021198, NP_067021 |
Reactivity | Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Bovine |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 29203 Da |
Gene ID | 58190 |
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Alias Symbol | NLIIF, SCP1, NIF3, NLI-IF |
Other Names | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, 3.1.3.16, Nuclear LIM interactor-interacting factor 3, NLI-IF, NLI-interacting factor 3, Small C-terminal domain phosphatase 1, SCP1, Small CTD phosphatase 1, CTDSP1, NIF3, NLIIF, SCP1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CTDSP1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | CTDSP1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CTDSP1 |
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Synonyms | NIF3, NLIIF, SCP1 |
Function | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. |
Cellular Location | Nucleus. Note=Colocalizes with RNA polymerase II |
Tissue Location | Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Marquet S.,et al.Mamm. Genome 11:755-762(2000).
Yeo M.,et al.J. Biol. Chem. 278:26078-26085(2003).
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Yeo M.,et al.Science 307:596-600(2005).

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