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>   首页   >   产品   >   一抗   >   微生物学   >   CLEC5A antibody - C-terminal region   

CLEC5A antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • 1 - CLEC5A antibody - C-terminal region AI14777

    WB Suggested Anti-CLEC5A Antibody Titration: 1.0 μg/ml
    Positive Control: THP-1 Whole Cell
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9NY25
Other Accession NM_013252, NP_037384
Reactivity Human, Rat, Pig, Dog, Horse, Bovine, Yeast
Predicted Human, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 21521 Da
Additional Information
Gene ID 23601
Alias Symbol CLECSF5, MDL-1, MDL1, MGC138304
Other Names C-type lectin domain family 5 member A, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1, MDL-1, CLEC5A, CLECSF5, MDL1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CLEC5A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCLEC5A antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLEC5A
Synonyms CLECSF5, MDL1
Function Functions as a positive regulator of osteoclastogenesis (By similarity). Cell surface receptor that signals via TYROBP (PubMed:10449773). Regulates inflammatory responses (By similarity).
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Highly expressed in bone marrow with lower levels in synovium, lung and bronchus (PubMed:20212065). Expressed in peripheral blood monocytes and in the monocyte/macrophage cell lines U- 937 and Mono-Mac-6, but not in cell lines of other origins (PubMed:10449773). Expression is down-regulated when monocytes differentiate into dendritic cells (PubMed:10449773)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Bakker A.B.H.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:9792-9796(1999).
Mueller A.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 424:157-164(2003).
Chen S.T.,et al.Nature 453:672-676(2008).
Watson A.A.,et al.J. Biol. Chem. 286:24208-24218(2011).

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