CLEC5A antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application ![]()
| WB |
---|---|
Primary Accession | Q9NY25 |
Other Accession | NM_013252, NP_037384 |
Reactivity | Human, Rat, Pig, Dog, Horse, Bovine, Yeast |
Predicted | Human, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 21521 Da |
Gene ID | 23601 |
---|---|
Alias Symbol | CLECSF5, MDL-1, MDL1, MGC138304 |
Other Names | C-type lectin domain family 5 member A, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1, MDL-1, CLEC5A, CLECSF5, MDL1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CLEC5A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | CLEC5A antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CLEC5A |
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Synonyms | CLECSF5, MDL1 |
Function | Functions as a positive regulator of osteoclastogenesis (By similarity). Cell surface receptor that signals via TYROBP (PubMed:10449773). Regulates inflammatory responses (By similarity). |
Cellular Location | Cell membrane; Single-pass type II membrane protein |
Tissue Location | Highly expressed in bone marrow with lower levels in synovium, lung and bronchus (PubMed:20212065). Expressed in peripheral blood monocytes and in the monocyte/macrophage cell lines U- 937 and Mono-Mac-6, but not in cell lines of other origins (PubMed:10449773). Expression is down-regulated when monocytes differentiate into dendritic cells (PubMed:10449773) |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Bakker A.B.H.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:9792-9796(1999).
Mueller A.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 424:157-164(2003).
Chen S.T.,et al.Nature 453:672-676(2008).
Watson A.A.,et al.J. Biol. Chem. 286:24208-24218(2011).

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