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>   首页   >   产品   >   一抗   >   信号转导   >   PTGDR antibody - C-terminal region   

PTGDR antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • 1 - PTGDR antibody - C-terminal region AI14652

    WB Suggested Anti-PTGDR Antibody Titration: 1.0 μg/ml
    Positive Control: THP-1 Whole Cell
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q13258
Other Accession NM_000953, NP_000944
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 40271 Da
Additional Information
Gene ID 5729
Alias Symbol AS1, ASRT1, DP, DP1, MGC49004, PTGDR1
Other Names Prostaglandin D2 receptor, PGD receptor, PGD2 receptor, Prostanoid DP receptor, PTGDR
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PTGDR antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPTGDR antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTGDR
Function Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). Involved in PLA2G3- dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Boie Y.,et al.J. Biol. Chem. 270:18910-18916(1995).
Martin A.L.,et al.Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
Heilig R.,et al.Nature 421:601-607(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Town M.H.,et al.Prostaglandins 25:13-28(1983).

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