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>   首页   >   产品   >   一抗   >   癌症   >   IL16 Antibody - C-terminal region   

IL16 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • 1 - IL16 Antibody - C-terminal region AI14649

    WB Suggested Anti-IL16 Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Spleen
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q14005
Other Accession NM_004513, NP_004504
Reactivity Human, Pig, Goat, Horse
Predicted Human, Pig, Goat, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 141752 Da
Additional Information
Gene ID 3603
Alias Symbol FLJ16806, FLJ42735, FLJ44234, LCF, NIL16, PRIL16, prIL-16
Other Names Pro-interleukin-16, Interleukin-16, IL-16, Lymphocyte chemoattractant factor, LCF, IL16
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-IL16 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsIL16 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL16
Function Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA- binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
Cellular Location [Interleukin-16]: Secreted. [Isoform 3]: Cytoplasm. Nucleus.
Tissue Location [Isoform 3]: Expressed in hemopoietic tissues, such as resting T-cells, but undetectable during active T-cell proliferation
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

REFERENCES

Bannert N.,et al.J. Biol. Chem. 278:42190-42199(2003).
Wang P.,et al.BMC Genomics 10:518-518(2009).
Kornfeld H.,et al.Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:671-675(2006).

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