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ABHD5 antibody - N-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q8WTS1 |
| Other Accession | NM_016006, NP_057090 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog, Horse, Bovine, Sheep |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Dog, Horse, Bovine, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39096 Da |
| Gene ID | 51099 |
|---|---|
| Alias Symbol | CDS, CGI58, IECN2, MGC8731, NCIE2 |
| Other Names | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5, 2.3.1.51, Abhydrolase domain-containing protein 5, Lipid droplet-binding protein CGI-58, ABHD5, NCIE2 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-ABHD5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | ABHD5 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ABHD5 (HGNC:21396) |
|---|---|
| Synonyms | NCIE2 |
| Function | Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfer of an acyl group on a lysophosphatidic acid (PubMed:18606822). Functions preferentially with 1-oleoyl- lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1- stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors (By similarity). Functions in phosphatidic acid biosynthesis (PubMed:18606822). May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2 (PubMed:16679289). Involved in keratinocyte differentiation (PubMed:18832586). Regulates lipid droplet fusion (By similarity). |
| Cellular Location | Cytoplasm. Lipid droplet {ECO:0000250|UniProtKB:Q9DBL9}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9DBL9}. Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity). |
| Tissue Location | Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons (at protein level). |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Bruno,C., (2008) Biochem. Biophys. Res. Commun. 369 (4), 1125-1128 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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