癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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EPB41 antibody - middle region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P11171 |
| Other Accession | NM_004437, NP_004428 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Yeast |
| Predicted | Human, Rabbit, Pig, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 97017 Da |
| Gene ID | 2035 |
|---|---|
| Alias Symbol | 4.1R, EL1, HE |
| Other Names | Protein 4.1, P4.1, 4.1R, Band 4.1, EPB4.1, EPB41, E41P |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-EPB41 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | EPB41 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EPB41 (HGNC:3377) |
|---|---|
| Synonyms | E41P |
| Function | Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127). |
| Cellular Location | Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Nucleus |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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