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Kcnh2 antibody - C-terminal region
Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | O35219 |
| Other Accession | NM_013569, NP_038597 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Dog, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 126886 Da |
| Gene ID | 16511 |
|---|---|
| Alias Symbol | AI326795, ERG1, LQT, Lqt2, M-erg, Merg1, merg1a, merg1b |
| Other Names | Potassium voltage-gated channel subfamily H member 2, Ether-a-go-go-related gene potassium channel 1, ERG-1, Eag-related protein 1, Ether-a-go-go-related protein 1, MERG, Voltage-gated potassium channel subunit Kv11.1, Kcnh2, Erg, Merg1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Kcnh2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Kcnh2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Kcnh2 {ECO:0000312|MGI:MGI:1341722} |
|---|---|
| Synonyms | Erg, Merg1 |
| Function | Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel (PubMed:9351446, PubMed:9351462). Characterized by unusual gating kinetics by producing relatively small outward currents during membrane depolarization and large inward currents during subsequent repolarization which reflect a rapid inactivation during depolarization and quick recovery from inactivation but slow deactivation (closing) during repolarization. Channel properties are modulated by cAMP and subunit assembly (PubMed:9351446, PubMed:9351462). Forms a stable complex with KCNE1 or KCNE2, and that this heteromultimerization regulates inward rectifier potassium channel activity (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q12809}; Multi-pass membrane protein |
| Tissue Location | [Isoform 1]: Expressed in heart, brain and testis and at low levels in lung. [Isoform 2]: Weakly expressed in all tissues. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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