癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CD26 (DPP IV / ADA-Binding Protein) Antibody - With BSA and Azide
Mouse Monoclonal Antibody [Clone 134-2C2 ]
- 产品详情
- 实验流程
- 背景知识
Application 
| IF, FC, IHC-F |
|---|---|
| Primary Accession | P27487 |
| Other Accession | 1803, 368912 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse / IgM, kappa |
| Clone Names | 134-2C2 |
| Calculated MW | 110 KDa |
| Other Names | Dipeptidyl peptidase 4, 3.4.14.5, ADABP, Adenosine deaminase complexing protein 2, ADCP-2, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, CD26, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV soluble form, DPP4, ADCP2, CD26 |
|---|---|
| Application Note | IF~~1:50~200 FC~~1:10~50 IHC-F~~N/A |
| Storage | Store at 2 to 8°C.Antibody is stable for 24 months. |
| Precautions | CD26 (DPP IV / ADA-Binding Protein) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Recognizes a glycoprotein of 110kDa, identified as CD26. It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.
REFERENCES
Fleischer B. CD26: a surface protease involved in T-cell activation. Immunol Today 1994, 15(4):180-184. | Abbott CA. et. al. Genomic organization, exact localization, and tissue expression of the human CD26 (dipeptidyl peptidase IV) gene. Immunogenetics 1994, 40:331-338. | Valenzuela A et. al. HIV-1 envelope gp120 and viral particles block adenosine deaminase binding to human CD26. Adv Exp Med Biol 1997, 421:185-192. | Cheng HC, et al. Lung endothelial dipeptidyl peptidase IV promotes adhesion and metastasis of rat breast cancer cells via tumor cell surface-associated fibronectin. J Biol Chem. 1998 273(37):24207-24015
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