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>   首页   >   产品   >   一抗   >   其他   >   Goat anti-CD83 (aa97-106) Antibody   

Goat anti-CD83 (aa97-106) Antibody

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, Pep-ELISA
Primary Accession Q01151
Other Accession NP_004224.1, NP_001035370.1, NP_001238830.1
Reactivity Human, Bovine
Host Goat
Clonality Polyclonal
Clone Names CD83
Calculated MW 23042 Da
Additional Information
Gene ID 9308
Other Names CD83; CD83 molecule; BL11; HB15; B-cell activation protein; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); cell surface protein HB15; cell-surface glycoprotein; hCD83
Dilution WB~~1:1000
Pep-ELISA~~N/A
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen This antibody is expected to recognize all reported isoforms (NP_004224.1; NP_001035370.1; NP_001238830.1).
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat anti-CD83 (aa97-106) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD83
Function Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHCII trafficking MARCHF8. Also inhibits MARCHF1 association with MHCII or CD86 to prevent their ubiquitination and subsequent degradation (PubMed:21220452). In addition, acts as an important modulator of protective responses against acute infections (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein.
Tissue Location Expressed by activated lymphocytes, Langerhans cells and activatd dendritic cells.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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