Goat anti-CD83 (aa97-106) Antibody
Peptide-affinity purified goat antibody
- 产品详情
- 实验流程
Application ![]()
| WB, Pep-ELISA |
---|---|
Primary Accession | Q01151 |
Other Accession | NP_004224.1, NP_001035370.1, NP_001238830.1 |
Reactivity | Human, Bovine |
Host | Goat |
Clonality | Polyclonal |
Clone Names | CD83 |
Calculated MW | 23042 Da |
Gene ID | 9308 |
---|---|
Other Names | CD83; CD83 molecule; BL11; HB15; B-cell activation protein; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); cell surface protein HB15; cell-surface glycoprotein; hCD83 |
Dilution | WB~~1:1000 Pep-ELISA~~N/A |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Immunogen | This antibody is expected to recognize all reported isoforms (NP_004224.1; NP_001035370.1; NP_001238830.1). |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat anti-CD83 (aa97-106) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD83 |
---|---|
Function | Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHCII trafficking MARCHF8. Also inhibits MARCHF1 association with MHCII or CD86 to prevent their ubiquitination and subsequent degradation (PubMed:21220452). In addition, acts as an important modulator of protective responses against acute infections (By similarity). |
Cellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Location | Expressed by activated lymphocytes, Langerhans cells and activatd dendritic cells. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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