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>   首页   >   产品   >   一抗   >   其他   >   CD24 Antibody   

CD24 Antibody

Mouse Monoclonal Antibody (Mab)

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC
Primary Accession P25063
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 121A1D5
Calculated MW 8083 Da
Additional Information
Gene ID 100133941
Gene Name CD24
Other Names Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, CD24, CD24, CD24A
Dilution IHC~~1:100~500
StorageMaintain refrigerated at 2-8°C.
Precautions CD24 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD24
Synonyms CD24A
Function May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin- like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells (PubMed:11313396). In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity (By similarity).
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Location B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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