Anti-PRMT6 Antibody (2C3-F1-G1)
Human Monoclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application
| WB, IHC, IF |
|---|---|
| Primary Accession | Q96LA8 |
| Reactivity | Human |
| Host | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 2C3-F1-G1 |
| Calculated MW | 41938 Da |
| Application & Usage | WB: HeLa and 293T cell lysate; IF: Hela cells; IHC: human breast cancer tissue |
|---|---|
| Other Names | HRMT1L6 |
| Target/Specificity | PRMT6 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Anti-PRMT6 Antibody (2C3-F1-G1) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. IPRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.
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