癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FOXM1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant FOXM1.
- 产品详情
- 文献引用 : 1
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q08050 |
| Other Accession | NM_202002 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3A9 |
| Calculated MW | 84283 Da |
| Gene ID | 2305 |
|---|---|
| Other Names | Forkhead box protein M1, Forkhead-related protein FKHL16, Hepatocyte nuclear factor 3 forkhead homolog 11, HFH-11, HNF-3/fork-head homolog 11, M-phase phosphoprotein 2, MPM-2 reactive phosphoprotein 2, Transcription factor Trident, Winged-helix factor from INS-1 cells, FOXM1, FKHL16, HFH11, MPP2, WIN |
| Target/Specificity | FOXM1 (NP_973731.1, 702 a.a. ~ 801 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | FOXM1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers. Lefebvre C, et al. Mol Syst Biol, 2010 Jun 8. PMID 20531406.FoxM1 mediates resistance to herceptin and paclitaxel. Carr JR, et al. Cancer Res, 2010 Jun 15. PMID 20530690.Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1. Alvarez-Fern?ndez M, et al. EMBO Rep, 2010 Jun. PMID 20379221.Attenuation of Forkhead signaling by the retinal determination factor DACH1. Zhou J, et al. Proc Natl Acad Sci U S A, 2010 Apr 13. PMID 20351289.EPS8 upregulates FOXM1 expression, enhancing cell growth and motility. Wang H, et al. Carcinogenesis, 2010 Jun. PMID 20351091.
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