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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   CNR2 Antibody (monoclonal) (M01)   

CNR2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CNR2.

     
  • 1 - CNR2 Antibody (monoclonal) (M01) AT1575a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (32.12 KDa) .
  • 1 - CNR2 Antibody (monoclonal) (M01) AT1575a
    Western Blot analysis of CNR2 expression in transfected 293T cell line by CNR2 monoclonal antibody (M01), clone 3C7.

    Lane 1: CNR2 transfected lysate(39.7 KDa).
    Lane 2: Non-transfected lysate.
  • 3 - CNR2 Antibody (monoclonal) (M01) AT1575a
    Immunofluorescence of monoclonal antibody to CNR2 on HeLa cell . [antibody concentration 10 ug/ml]
  • 10 - CNR2 Antibody (monoclonal) (M01) AT1575a
    Detection limit for recombinant GST tagged CNR2 is 0.1 ng/ml as a capture antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, E
Primary Accession P34972
Other Accession NM_001841.1
Reactivity Human
Host mouse
Clonality monoclonal
Isotype IgG1 Kappa
Clone Names 3C7
Calculated MW 39681 Da
Additional Information
Gene ID 1269
Other Names Cannabinoid receptor 2, CB-2, CB2, hCB2, CX5, CNR2, CB2A, CB2B
Target/Specificity CNR2 (NP_001832.1, 302 a.a. ~ 360 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
IF~~1:50~200
E~~N/A
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCNR2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

REFERENCES

1.Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity.Brocato B, Zoerner AA, Janjetovic Z, Skobowiat C, Gupta S, Moore Ii BM, Slominski A, Zhang J, Schenone M, Phinehas R, Ferry RJ Jr, Dick E Jr, Hubbard GB, Mari G, Schlabritz-Loutsevitch NPlacenta. 2013 Sep 2. pii: S0143-4004(13)00692-9. doi: 10.1016/j.placenta.2013.08.007.

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